Pesquisa | BVS Integralidade em Saúde

1.

Complex effects of sequence variants on lipid levels and coronary artery disease.

Snaebjarnarson, Audunn S; Helgadottir, Anna; Arnadottir, Gudny A; Ivarsdottir, Erna V; Thorleifsson, Gudmar; Ferkingstad, Egil; Einarsson, Gudmundur; Sveinbjornsson, Gardar; Thorgeirsson, Thorgeir E; Ulfarsson, Magnus O; Halldorsson, Bjarni V; Olafsson, Isleifur; Erikstrup, Christian; Pedersen, Ole B; Nyegaard, Mette; Bruun, Mie T; Ullum, Henrik; Brunak, Søren; Iversen, Kasper Karmark; Christensen, Alex Hoerby; Olesen, Morten S; Ghouse, Jonas; Banasik, Karina; Knowlton, Kirk U; Arnar, David O; Thorgeirsson, Gudmundur; Nadauld, Lincoln; Ostrowski, Sisse Rye; Bundgaard, Henning; Holm, Hilma; Sulem, Patrick; Stefansson, Kari; Gudbjartsson, Daniel F.

Cell ; 186(19): 4085-4099.e15, 2023 09 14.

Artigo em Inglês | MEDLINE | ID: mdl-37714134

2.

The Born in Guangzhou Cohort Study enables generational genetic discoveries.

Huang, Shujia; Liu, Siyang; Huang, Mingxi; He, Jian-Rong; Wang, Chengrui; Wang, Tianyi; Feng, Xiaotian; Kuang, Yashu; Lu, Jinhua; Gu, Yuqin; Xia, Xiaoyan; Lin, Shanshan; Zhou, Wenhao; Fu, Qiaomei; Xia, Huimin; Qiu, Xiu.

Nature ; 626(7999): 565-573, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38297123

3.

Quasi-experimental evaluation of a nationwide diabetes prevention programme.

Lemp, Julia M; Bommer, Christian; Xie, Min; Michalik, Felix; Jani, Anant; Davies, Justine I; Bärnighausen, Till; Vollmer, Sebastian; Geldsetzer, Pascal.

Nature ; 624(7990): 138-144, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37968391

4.

Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.

Wang, Ju-Qiong; Li, Liang-Liang; Hu, Ao; Deng, Gang; Wei, Jian; Li, Yun-Feng; Liu, Yuan-Bin; Lu, Xiao-Yi; Qiu, Zhi-Ping; Shi, Xiong-Jie; Zhao, Xiaolu; Luo, Jie; Song, Bao-Liang.

Nature ; 608(7922): 413-420, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35922515

5.

Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.

Hindy, George; Dornbos, Peter; Chaffin, Mark D; Liu, Dajiang J; Wang, Minxian; Selvaraj, Margaret Sunitha; Zhang, David; Park, Joseph; Aguilar-Salinas, Carlos A; Antonacci-Fulton, Lucinda; Ardissino, Diego; Arnett, Donna K; Aslibekyan, Stella; Atzmon, Gil; Ballantyne, Christie M; Barajas-Olmos, Francisco; Barzilai, Nir; Becker, Lewis C; Bielak, Lawrence F; Bis, Joshua C; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L; Bottinger, Erwin; Bowden, Donald W; Bown, Matthew J; Brody, Jennifer A; Broome, Jai G; Burtt, Noël P; Cade, Brian E; Centeno-Cruz, Federico; Chan, Edmund; Chang, Yi-Cheng; Chen, Yii-Der I; Cheng, Ching-Yu; Choi, Won Jung; Chowdhury, Rajiv; Contreras-Cubas, Cecilia; Córdova, Emilio J; Correa, Adolfo; Cupples, L Adrienne; Curran, Joanne E; Danesh, John; de Vries, Paul S; DeFronzo, Ralph A; Doddapaneni, Harsha; Duggirala, Ravindranath; Dutcher, Susan K; Ellinor, Patrick T; Emery, Leslie S.

Am J Hum Genet ; 109(1): 81-96, 2022 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-34932938

6.

Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort.

Lauber, Chris; Gerl, Mathias J; Klose, Christian; Ottosson, Filip; Melander, Olle; Simons, Kai.

PLoS Biol ; 20(3): e3001561, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35239643

7.

An integrative systems genetic analysis of mammalian lipid metabolism.

Parker, Benjamin L; Calkin, Anna C; Seldin, Marcus M; Keating, Michael F; Tarling, Elizabeth J; Yang, Pengyi; Moody, Sarah C; Liu, Yingying; Zerenturk, Eser J; Needham, Elise J; Miller, Matthew L; Clifford, Bethan L; Morand, Pauline; Watt, Matthew J; Meex, Ruth C R; Peng, Kang-Yu; Lee, Richard; Jayawardana, Kaushala; Pan, Calvin; Mellett, Natalie A; Weir, Jacquelyn M; Lazarus, Ross; Lusis, Aldons J; Meikle, Peter J; James, David E; de Aguiar Vallim, Thomas Q; Drew, Brian G.

Nature ; 567(7747): 187-193, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30814737

8.

Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study.

Lu, Jiawen; Wang, Zhenqian; Zhang, Jiaying; Jiao, Feng; Zou, Chenfeng; Han, Liyuan; Jiang, Guozhi.

J Lipid Res ; 65(4): 100528, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38458338

9.

Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease.

Kim, Young-Chae; Qi, Ming; Dong, Xingchen; Seok, Sunmi; Sun, Hao; Kemper, Byron; Fu, Ting; Kemper, Jongsook Kim.

J Biol Chem ; 299(8): 104946, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37348559

10.

Once-Weekly Semaglutide in Adults with Overweight or Obesity.

Wilding, John P H; Batterham, Rachel L; Calanna, Salvatore; Davies, Melanie; Van Gaal, Luc F; Lingvay, Ildiko; McGowan, Barbara M; Rosenstock, Julio; Tran, Marie T D; Wadden, Thomas A; Wharton, Sean; Yokote, Koutaro; Zeuthen, Niels; Kushner, Robert F.

N Engl J Med ; 384(11): 989-1002, 2021 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-33567185

11.

Serum lipid reference values recommended during a twin pregnancy and evaluating its association with perinatal outcomes.

Huang, Jiaqi; Meng, Xinlu; Li, Jiaxin; Gong, Xiaoli; Wu, Tianchen; Shi, Huifeng; Li, Xiaona; Wang, Xueju; Yang, Jing; Zhao, Yangyu; Wei, Yuan.

BMC Pregnancy Childbirth ; 24(1): 18, 2024 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-38166706

12.

Association of lipid profile and obesity in patients with polycystic ovary syndrome.

Parveen, Sadaf; Khan, Saba; Khan, Mohammad Mustufa; Gupta, Bhavana; Ahmad, Ausaf; Alam, Roshan.

Endocr Regul ; 58(1): 83-90, 2024 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-38656255

13.

Age effect on the shared etiology of glycemic traits and serum lipids: evidence from a Chinese twin study.

Wang, Y; Hong, X; Cao, W; Lv, J; Yu, C; Huang, T; Sun, D; Liao, C; Pang, Y; Pang, Z; Yu, M; Wang, H; Wu, X; Liu, Y; Gao, W; Li, L.

J Endocrinol Invest ; 47(3): 535-546, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-37524979

14.

Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci.

Francis, Michael; Li, Changwei; Sun, Yitang; Zhou, Jingqi; Li, Xiang; Brenna, J Thomas; Ye, Kaixiong.

PLoS Genet ; 17(3): e1009431, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33760818

15.

Divergent low-density lipoprotein receptor (LDLR) linked to low VSV G-dependent viral infectivity and unique serum lipid profile in zebra finches.

Velho, Tarciso A F; Lovell, Peter V; Friedrich, Samantha R; Olson, Christopher R; Miles, Joshua; Mueller, Paul A; Tavori, Hagai; Fazio, Sergio; Lois, Carlos; Mello, Claudio V.

Proc Natl Acad Sci U S A ; 118(18)2021 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-33903244

16.

A systematic review and meta-analysis of serum lipid concentrations in people with Down syndrome.

Gastelum Guerrero, Carolina; Cháidez Fernández, Yuridia Lizet; Magaña Ordorica, Dalia; Berger, Heidi; Vazquez Landrove, Marilyn; Guadrón Llanos, Alma; Angulo Rojo, Carla; Magaña Gómez, Javier.

J Intellect Disabil Res ; 68(6): 553-563, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38404114

17.

Effects of high-intensity interval training and its different protocols on lipid profile and glycaemic control in type 2 diabetes: A meta-analysis.

Cavalli, Nandiny Paula; de Mello, Mariana Brondani; Righi, Natiele Camponogara; Schuch, Felipe Barreto; Signori, Luis Ulisses; da Silva, Antônio Marcos Vargas.

J Sports Sci ; 42(4): 333-349, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38531052

18.

Lipid profiling of brain tissue and blood after traumatic brain injury: A review of human and experimental studies.

Nessel, Isabell; Michael-Titus, Adina T.

Semin Cell Dev Biol ; 112: 145-156, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33036880

19.

Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.

Wang, Xiaolin; Yang, Yanfang; Zhao, Dan; Zhang, Shuang; Chen, Yi; Chen, Yuanli; Feng, Ke; Li, Xiaoju; Han, Jihong; Iwakiri, Yasuko; Duan, Yajun; Yang, Xiaoxiao.

J Biol Chem ; 298(2): 101561, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34998825

20.

Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia.

Santos, Raul D; Ruzza, Andrea; Hovingh, G Kees; Wiegman, Albert; Mach, François; Kurtz, Christopher E; Hamer, Andrew; Bridges, Ian; Bartuli, Andrea; Bergeron, Jean; Szamosi, Tamás; Santra, Saikat; Stefanutti, Claudia; Descamps, Olivier S; Greber-Platzer, Susanne; Luirink, Ilse; Kastelein, John J P; Gaudet, Daniel.

N Engl J Med ; 383(14): 1317-1327, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-32865373

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